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Fortunately, there are many specialized options available for opiate detox; these include the use of Buprenorphine (Subutex/ Suboxone) and Naltrexone (ReVia, Vivitrol). The use of such medications eases the discomfort of opiate withdrawal symptoms. Indeed, most patients can work fulltime while undergoing this detox treatment. And outpatient opiate detox costs significantly less than what an inpatient detox costs. Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err on the side of caution and allow FDA do its job and demand some research be done so that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants investing in this drug to get a year, lost weight within four weeks and have kept the weight off during the entire 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which may make them more potent and safer. Combo-pilling will be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular could be the fact that as of right now there are no long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and must not be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heartrate, and really should not be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure levels, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. Other people who must avoid using Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave should not be prescribed for ladies who are pregnant or attempting to become pregnant.